宋昕玥

时间：2022-08-18 作者： 来源：医学院 浏览：10

个人简介：

宋昕玥，教授，女，1988年10月生，2016年毕业于中国科学院大学，获理学博士学位，博士生导师，研究方向为肿瘤标志物的检测、成像及肿瘤诊疗一体化研究。


承担的主要教学、科研项目:

  1. 国家自然科学基金面上项目，22176081，基于级联信号放大策略检测环境水样品中痕量四环素及其抗性基因的研究，2022/01-2025/12，60万，在研，主持

  2. 国家自然科学基金青年项目，21605068，基于中空纤维的电化学生物传感技术分离和检测miRNA一体化研究，2017/01-2019/12，20万，结题，主持

  3. 山东省自然科学基金面上项目，ZR2021MB071，基于光敏剂分子信标构建生物传感介导的上转换光动力诊疗体系的研究，2021/01-2024/12，10万，在研，主持

  4. 山东省重点研发计划，2017GGX40110，高容量、大倍率三元镍钴锰酸锂622型锂离子电池正极材料生产技术，2017/08-2020/07，25万，结题，主持

  5. 山东省临沂市重点研发计划，2016GG027，内置乳酸全息传感器的智能隐形眼镜的研究与应用，2016/01-2017/12，10万，结题，主持

  6. 中国博士后第61批面上资助，2017M612183，上转换纳米荧光探针实现癌细胞多模式成像和诊疗一体化研究，2016.9-2018.7，结题，主持


代表性学术成果:

论文：

  1. Tao Yan, Linlin Ren, Fengyan Li, Feng Tian, Chengfang Jiang, Qi Wang, Xinyue Song*, Shusheng Zhang*, Construction of a sequentially responsive nanocarrier for chemotherapy and cascade amplified NIR photodynamic therapy, Chemical Communications, 2022, 58:1617-1620

  2. Xinyue Song, Tao Yan, Feng Tian, Fengyan Li, Linlin Ren, Qiong Li, Shusheng Zhang*, Aptamer functionalized upconversion nanotheranostic agent with nuclear targeting as the highly localized drug-delivery system of doxorubicin, Frontiers in Bioengineering and Biotechnology, 2021, 9: 639487.

  3. Caixia Wang, Bo Wu, Yuting Wu, Xinyue Song, Shusheng Zhang,* Zhihong Liu*, Camouflaging nanoparticles with brain metastatic tumor cell membranes: a new strategy to traverse blood-brain barrier for imaging and therapy of brain tumors, Advanced Functional Materials, 2020, 30: 1909369.

  4. Xinyue Song, Huairong Zhang, Tao Yan, Tongtong Hong, Shusheng Zhang*, Controllable growth and assembling strategies based on nanomaterials for targeted and precise therapy of malignant cancers, Chinese Journal of Chemistry, 2020, 38 (12): 1489-1496.

  5. Tao Yan, Zhenhua Liu, Xinyue Song, Shusheng Zhang*, Construction and Development of Tumor Microenvironment Stimulus-Responsive Upconversion Photodynamic Diagnosis and Treatment System, Acta Chim. Sinica 2020, 78: 657-669.

  6. Tongtong Hong,Yanxialei Jiang,Zihong Yue,Xinyue Song*,Zonghua Wang*, Shusheng Zhang, Construction of multicolor upconversion nanotheranostic agent for in-situ cooperative photodynamic therapy for deep-seated malignant tumors, Frontiers in Chemistry, 2020, 8: 52.

  7. Xinyue Song, Zihong Yue, Tongtong Hong, Zonghua Wang, Shusheng Zhang*, Sandwich-structured upconversion nanoprobes coated with a thin silica layer for mitochondria-targeted cooperative photodynamic therapy for solid malignant tumors, Analytical Chemistry, 2019, 91 (13): 8549-8557.

  8. Shuzhen Yue, Xinyue Song, Weiling Song, Sai Bi*, An enzyme-free molecular catalytic device: dynamically self-assembled DNA dendrimers for in situ imaging of microRNAs in live cells, Chemical Science, 2019,10: 1651-1658

  9. Yawen Ding, Xinyue Song*, Juan Chen, Analysis of pesticide residue in tomatoes by carbon nanotubes/β-cyclodextrin nanocomposite reinforced hollow fiber coupled with HPLC, Journal of Food Science, 2019, 84(6): 1651-1659.

  10. Zihong Yue, Tongtong Hong, Xinyue Song*, Zonghua Wang*, Construction of a targeted photodynamic nanotheranostic agent using upconversion nanoparticles coated with the ultrathin silica layer, Chemical Communications, 2018, 54: 10618-10621.

  11. Xinyue Song, Zihong Yue, Jiayu Zhang, Yanxialei Jiang, Zonghua Wang,     Shusheng Zhang*, Multicolor upconversion nanoprobe based on dual luminescenceresonance energy transfer assay for simultaneous detection andbioimaging of [Ca2+]i and pHi in living cells, Chemistry A European Journal, 2018, 24: 6458-6463.

  12. XinYue Song, Jiayu Zhang, Zihong Yue, Zonghua Wang, Zhihong Liu*, Shusheng Zhang*, Dual-activator codoped upconversion nanoprobe with core-multishell structure for in vitro and in vivo detection of hydroxyl radical, Analytical Chemistry, 2017, 89(20): 11021-11026.

  13. Xinyue Song, Juan Chen, Yanping Shi, Different configurations of carbon nanotubes reinforced solid-phase microextraction techniques and their applications in the environmental analysis, Trends in Analytical Chemistry 86 (2017) 263-275

专著情况

[1] Shusheng Zhang, Sai Bi, Xinyue Song, Nucleic Acid Amplifification Strategies for Biosensing, Bioimaging and Biomedicine, Springer Nature, ISBN 978-981-13-7043-4

[2] 张书圣，毕赛，宋昕玥，功能化纳米材料在生化分析中的应用，科学出版社，ISBN: 978-7-03-064036-9


专利：

[1] 宋昕玥，张家瑀，王庆利，β-环糊精修饰全息传感器定量分析生物试样中布洛芬的方法，专利授权号：ZL201611052102.3



电子邮箱：songxinyue428@163.com


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