崔玉磊

时间:2022-08-18 作者: 来源:医学院 浏览:3181


个人简介

崔玉磊,副教授,男,199006月生,2019年毕业于中国科学院大学,获博士学位,硕士生导师。研究方向为天然药用资源开发与利用。山东省高等学校“青创团队计划”团队负责人,山东省博士后创新人才,临沂市食品工业协会专家临沂市乡村振兴科技特派员。担任国际SCI期刊PhytomedicinePhytotherapy ResearchJournal of EthnopharmacologyFood ChemistryIndustrial Crops and Products等审稿人。

承担的主要教学、科研项目:

[1]山东省自然科学基金面上项目,ZR2024MH2482025-2027年,在研,主持。

[2]山东省高等学校青创科技支持计划,2023KJ2172024-2026年,在研,主持。

[3]国家自然科学基金青年项目,822047622023-2025年,在研,主持。

[4]中国博士后基金面上资助项目,2022M7219842023-2024年,结题,主持。

[5]米兰体育官网入口高水平博士启动基金,LYDX2019BS0552019-2024, 在研,主持。

代表性学术成果:

[1]Na Shen, Ziyao Shao, Huawei Xin, Fengyuan Che*, Yulei Cui*, Exploring TβRI inhibitors from Arenaria kansuensis based on 3D-QSAR, molecular docking and molecular dynamics simulation methods and its anti-pulmonary fibrosis molecular mechanism validation, Journal of Ethnopharmacology, 337 (2025) 118788.

[2]Na Shen, Yanxia Liu, Ziyao Shao, Huawei Xin, Jun Ma,* Yulei Cui* PHYTOCHEMICAL CONSTITUENTS FROM THE GREEN WALNUT HUSK OF Juglans mandshurica, 2024, 60 (6), 1123-1125.

[3]Yao Liu, Na Shen, Huawei Xin, Lili Yu, Qing Xu, Yulei Cui*. Unsaturated fatty acids in natural edible resources, a systematic review of classification, resources, biosynthesis, biological activities and application, Food Bioscience, 53 (2023): 102790.

[4] Yanxia Liu, Wanqing Sun, Na Shen, Wenhua Hao, Huawei Xin, Fengyuan Che, Yulei Cui*. Network pharmacology and molecular docking combined with widely targeted metabolomics to elucidate the potential compounds and targets of Euphorbia helioscopia seeds for the treatment of pulmonary fibrosis, Computers in Biology and Medicine, 160(2023):107007.

[5] Na Shen , Yuanrong Li, Yanxia Liu, Yao Liu, Huawei Xin, Yulei Cui*. Gypsophila oldhamiana leaves as a potential industrial resource of lipids, alkaloids, flavonoids and anti-osteoporosis components. Industrial Crops and Products,196(2023): 116510.

[6] Yanxia Liu, Huawei Xin, Wenli Li, Na Shen*, Yulei Cui*,Ginkgo biloba endopleura: An unexplored industrial waste as a potential source of flavonoids, lipids and anti-lung cancer compounds, Industrial Crops and Products,189(2022): 115851.

[7] Na Shen, Jiani Ren, Yanxia Liu, Wanqing Sun, Yuanrong Li, Huawei Xin*, Yulei Cui*. Natural edible pigments: A comprehensive review of resource, chemical classification, biosynthesis pathway, separated methods and application. Food Chemistry. 403(2022):134422.

[8] Na Shen, Yuan Chen*, Fengxia Guo, Yulei Cui*, Mu Wei, Zhiqiang Cheng. Influence of different drying methods coupled with different process modes on physicochemical qualities and anthraquinones contents of Rheum palmatum L.,LWT-FOOD SCIENCE AND TECHNOLOGY,170 (2022):114021.

[9]Yanxia Liu, Huawei Xin, Yunchao Zhang, Fengyuan Che, Na Shen*, Yulei Cui*. Leaves, seeds and exocarp of Ginkgo biloba L. (Ginkgoaceae): A Comprehensive Review of Traditional Uses, phytochemistry, pharmacology, resource utilization and toxicity[J]. Journal of Ethnopharmacology, 2022, 298 (2022): 115645.

[10] Shen Na, Liu Yanxia , Cui Yulei*, Xin Huawei. Large-scale targetedly isolation of biflavonoids with high purity from industrial waste Ginkgo biloba exocarp using two-dimensional chromatography coupled with macroporous adsorption resin enrichment[J]. Industrial Crops & Products, 2022, 175 (2022): 114264.

[11] Cui Yulei, Xin Huawei , Tao Yanduo , Mei Lijuan*, Wang Zhen*. Arenaria kansuensis attenuates pulmonary fibrosis in mice via the activation of Nrf2 pathway and the inhibition of NF‐kB/TGF‐beta1/Smad2/3 pathway[J]. Phytotherapy Research, 2020. 35(2):974-986.

[12] Cui Yulei, Jiang Lei, Yu Ruitao, Shao Yun, Mei Lijuan*, Tao Yanduo*. β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial mesenchymal transition. Journal of Ethnopharmacology. 2019, 243(2019): 112096.

[13] Cui Yulei, Shao Yun, Wang Qilan, Mei Lijuan, Tao Yanduo*, Purification of Flavonolignan Diastereoisomers from Arenaria kansuensis by Two-Dimensional Liquid Chromatography Combined with Solid-Phase Extraction. Journal of Chromatographic Science, 2019, 57(5): 418-425.

[14] Cui Yulei, Jiang Lei, Shao Yun Mei Lijuan*, Tao Yanduo*, Anti-alcohol liver disease effect of Gentianae macrophyllae extract through MAPK/JNK/p38 pathway. Journal of Pharmacy and Pharmacology, 2019, 71(2): 240-250.

[15] Cui, Yulei, Tao, Yanduo, Jiang, Lei, Shen, Na, Wang, Shuo, Wen, Huaixiu, Liu, Zenggen*. Antihypoxic activities of constituents from Arenaria kansuensis. Phytomedicine, 2018, 38, 175-182.

[16] Cui Yulei, Zhao Xiaoying, Mei Lijuan, Pei Jinjin, Wang Shuo, Shao Yun, Tao Yanduo, Zhang Xiaoling*, Jiang Lei*. Osteon myospalacem baileyi attenuates osteoclast differentiation through rankle induced NFAT pathways. Journal of Ethnopharmacology, 2018, 213: 65-71.

专利:

[1]甘肃蚤缀的用途. 202010518923.1. 崔玉磊,沈娜,辛化伟,王振,李春雷。

[2]β-咔啉生物碱 GAK 在制备治疗和/或预防肺纤维化的产品中的途.202110088766.X。崔玉磊,沈娜,辛化伟。

指导学生大学生创新创业训练计划项目:

[1]米兰体育官网入口,银杏外种皮的化学成分及其抗菌活性研究,2021年,X2021104522 12,任佳妮,结题

[2]米兰体育官网入口,基于广泛靶向代谢组学、网络药理学和计算机辅助药物设计探究泽漆种子治疗肺纤维化的潜在物质基础和作用机制, 2022年,X202210452201,孙婉晴,结题

[3]山东省教育厅,银杏内种皮抗肺纤维化活性成分及其作用机制研究,2023年,

S202310452124,刘耀,结题。

指导学生获奖:

[1]刘艳霞,2020级研究生,2023届山东省优秀毕业生

[2]刘耀、孙婷、牟晶一、张圆圆,2020级药学本科生,山东省大学生医药生物技术技能大赛创新大赛,三等奖。

[3]任住妮、李园蓉、彻婉晴,2019级药学本科生,第十三届山东省大学生科技节—“鲁南制药杯”第八届山东省大学生医药生物技术技能大赛—创新创业竞赛,三等奖。


电子邮箱:cuiyulei@lyu.edu.cn


欢迎对天然药用资源开发与利用感兴趣的同学报考本课题组研究生


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